Baylor College of Medicine

Development, Disease Models, & Therapeutics


One Baylor Plaza, MS: BCM215

MC 385

Houston, TX 77030

United States





Program Information

Degrees Offered:


Format: Campus

Program Description:

Working at the interface of developmental biology, physiology, health and disease, our researchers utilize diverse disease models to understand the biology of human diseases that can impact all stages of life -- from hereditary and congenital birth defects to degenerative diseases of old age -- and develop diagnostic and therapies to treat them.

Our faculty use animals as diverse as slime molds, fruit flies, nematode worms, slime molds, frogs, fish, chickens, mice and humans to understand and model human diseases and to develop diagnostics and therapies to treat them.  Many of our faculty make use of concepts in developmental and molecular biology, genetics, physiology, imaging, stem cells and regenerative medicine, but we also emphasize an understanding of how tissue systems function in the adult.

We take advantage of the resources of the world's largest medical center to connect basic researchers and clinicians so that research questions are addressed through multiple disciplines and perspectives. 

You will have the opportunity to explore all aspects of disease, from fundamental biological principles to the design and development of therapeutics. 

Working within our research model, our interdisciplinary faculty pursues diverse areas of research. While many of these areas of focus overlap with those of other programs at BCM and elsewhere, what makes our program unique is our approach.

Research areas include the following:

  • Aging
  • Animal models of human disease
  • Biological imaging of humans and animal models
  • Biophysics, bioengineering and tissue engineering
  • Cardiovascular and vascular development, physiology and disease
  • Cellular development and function including cell division, cancer biology, stem cell biology,  stem cell engineering, and cell lineage specification and differentiation
  • Developmental biology, embryology and birth defects
  • Epigenetic regulation of development and epigenetics of disease
  • Immune system development, function and disease including immunobiology, immune disorders, inflammation and inflammatory disease
  • Liver, kidney and pancreas development, function and diseases
  • Metabolism and metabolic disorders
  • Nervous and sensory systems development, function and disease including neurodegeneration, neuromuscular physiology, neurological disease and autism spectrum disorders
  • Reproductive biology, reproductive disorders and fertility
  • Therapeutic approaches including drug discovery, experimental surgery and neurosurgery, clinical trials, gene therapy, molecular medicine and immunotherapy

Facts & Figures

Classification: Specialized Institution—Medical school or medical center

Locale: Large City

Size & Settings: 1,000-2,999

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